Ingénieur de Recherche – Caen
Yannick HOMMET
28 documents
Articles dans une revue
- Paul Prunotto, Pauline Marie, Laurent Lebouvier, Yannick Hommet, Denis Vivien, et al.. The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons. Cell Death and Disease, 2024, 15 (4), pp.261. ⟨10.1038/s41419-024-06655-0⟩. ⟨hal-05509814⟩
- Jonathane Furon, Mervé Yetim, Elsa Pouettre, Sara Martinez de Lizarrondo, Eric Maubert, et al.. Blood tissue Plasminogen Activator (tPA) of liver origin contributes to neurovascular coupling involving brain endothelial N-Methyl-D-Aspartate (NMDA) receptors. Fluids and Barriers of the CNS, 2023, 20 (1), pp.11. ⟨10.1186/s12987-023-00411-w⟩. ⟨hal-05509804⟩
- Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lazarrondo, Laurent Lebouvier, et al.. Correction to: The choroid plexus: A door between the blood and the brain for tissue-type plasminogen activator. Fluids and Barriers of the CNS, 2022, 19 (1), pp.83. ⟨10.1186/s12987-022-00383-3⟩. ⟨hal-05509952⟩
- Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lizarrondo, Laurent Lebouvier, et al.. The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator. Fluids and Barriers of the CNS, 2022, 19 (1), pp.80. ⟨10.1186/s12987-022-00378-0⟩. ⟨hal-05509831⟩
- Matthieu Lépine, Sara Douceau, Gabrielle Devienne, Paul Prunotto, Sophie Lenoir, et al.. Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure. BMC Biology, 2022, 20 (1), pp.218. ⟨10.1186/s12915-022-01419-8⟩. ⟨hal-05509836⟩
- Sara Douceau, Eloïse Lemarchand, Yannick Hommet, Laurent Lebouvier, Charlène Joséphine, et al.. PKCδ-positive GABAergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety. Molecular Psychiatry, 2022, 27 (4), pp.2197-2205. ⟨10.1038/s41380-022-01455-4⟩. ⟨hal-05509838⟩
- Eugénie Garnier, Damien Levard, Carine Ali, Izaskun Buendia, Yannick Hommet, et al.. Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor‐dependent mechanisms. Journal of Thrombosis and Haemostasis, 2021, 19 (9), pp.2235-2247. ⟨10.1111/jth.15414⟩. ⟨hal-05509852⟩
- Antoine Anfray, Antoine Drieu, Vincent Hingot, Yannick Hommet, Mervé Yetim, et al.. Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors. Journal of Cerebral Blood Flow and Metabolism, 2019, 40 (10), pp.2038-2054. ⟨10.1177/0271678X19883599⟩. ⟨hal-05509854⟩
- Nolwenn Pasquet, Sara Douceau, Mickael Naveau, Flavie Lesept, Morgane Louessard, et al.. Tissue-Type Plasminogen Activator Controlled Corticogenesis Through a Mechanism Dependent of NMDA Receptors Expressed on Radial Glial Cells. Cerebral Cortex, 2019, 29 (6), pp.2482-2498. ⟨10.1093/cercor/bhy119⟩. ⟨hal-05509860⟩
- Sophie Lenoir, Alexandre Varangot, Laurent Lebouvier, Thierry Galli, Yannick Hommet, et al.. Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA). Frontiers in Cellular Neuroscience, 2019, 13, ⟨10.3389/fncel.2019.00164⟩. ⟨hal-05509856⟩
- Benoit Roussel, Yannick Hommet, Richard Macrez, Torsten Schulz, Karl-Uwe Petersen, et al.. PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAα1) prevents the passage of tissuetype plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity. Thrombosis and Haemostasis, 2017, 102 (09), pp.606-608. ⟨10.1160/TH09-02-0114⟩. ⟨hal-05509924⟩
- Camille Leonetti, Richard Macrez, Mathilde Pruvost, Yannick Hommet, Jérémie Bronsard, et al.. Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination. Molecular Neurodegeneration, 2017, 12 (1), pp.20. ⟨10.1186/s13024-017-0160-5⟩. ⟨hal-05509865⟩
- Didier Leys, Yannick Hommet, Clémence Jacquet, Solène Moulin, Igor Sibon, et al.. Proportion of single-chain recombinant tissue plasminogen activator and outcome after stroke. Neurology, 2016, 87 (23), pp.2416-2426. ⟨10.1212/WNL.0000000000003399⟩. ⟨hal-05509870⟩
- Oscar Marcos-Contreras, Sara Martinez de Lizarrondo, Isabelle Bardou, Cyrille Orset, Mathilde Pruvost, et al.. Hyperfibrinolysis increases blood–brain barrier permeability by a plasmin- and bradykinin-dependent mechanism. Blood, 2016, 128 (20), pp.2423-2434. ⟨10.1182/blood-2016-03-705384⟩. ⟨hal-05509875⟩
- Flavie Lesept, Arnaud Chevilley, Julie Jezequel, Laurent Ladépêche, Richard Macrez, et al.. Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors. Cell Death and Disease, 2016, 7 (11), pp.e2466-e2466. ⟨10.1038/cddis.2016.279⟩. ⟨hal-05509868⟩
- T Bertrand, F Lesept, A Chevilley, S Lenoir, M Aimable, et al.. Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR. Cell Death and Disease, 2015, 6 (10), pp.e1924-e1924. ⟨10.1038/cddis.2015.296⟩. ⟨hal-05509903⟩
- Sighild Lemarchant, Mathilde Pruvost, Marie Hébert, Maxime Gauberti, Yannick Hommet, et al.. tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiology of Disease, 2014, 66, pp.28-42. ⟨10.1016/j.nbd.2014.02.005⟩. ⟨hal-05509908⟩
- J. Parcq, T. Bertrand, A.F. Baron, Yannick Hommet, E. Anglès-Cano, et al.. Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain. Journal of Thrombosis and Haemostasis, 2013, 11 (3), pp.539-546. ⟨10.1111/jth.12128⟩. ⟨hal-05509911⟩
- J Parcq, T Bertrand, A Montagne, A Baron, R Macrez, et al.. Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity. Cell Death and Differentiation, 2012, 19 (12), pp.1983-1991. ⟨10.1038/cdd.2012.86⟩. ⟨hal-05509913⟩
- Amandine Baron, Yannick Hommet, Frédéric Cassé, Denis Vivien. Tissue‐type plasminogen activator induces plasmin‐dependent proteolysis of intracellular neuronal nitric oxide synthase. Biology of the Cell, 2012, 102 (10), pp.539-547. ⟨10.1042/BC20100072⟩. ⟨hal-05509921⟩
- Richard Macrez, Pauline Obiang, Maxime Gauberti, Benoit Roussel, Amandine Baron, et al.. Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl- d -Aspartate Receptors Reduce Stroke Damages and Extend the Therapeutic Window of Thrombolysis. Stroke, 2011, 42 (8), pp.2315-2322. ⟨10.1161/STROKEAHA.110.606293⟩. ⟨hal-05509915⟩
- Benoit Roussel, Caroline Mysiorek, Ari Rouhiainen, Amandine Jullienne, Jerome Parcq, et al.. HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator. Journal of Cell Science, 2011, 124 (12), pp.2070-2076. ⟨10.1242/jcs.084392⟩. ⟨hal-05509916⟩
- Fernando Correa, Maxime Gauberti, Jérôme Parcq, Richard Macrez, Yannick Hommet, et al.. Tissue plasminogen activator prevents white matter damage following stroke. Journal of Experimental Medicine, 2011, 208 (6), pp.1229-1242. ⟨10.1084/jem.20101880⟩. ⟨hal-05509917⟩
- Maxime Culot, Caroline Mysiorek, Mila Renftel, Benoit Roussel, Yannick Hommet, et al.. Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: An in vitro study. Brain Research, 2009, 1294, pp.144-152. ⟨10.1016/j.brainres.2009.07.035⟩. ⟨hal-05509928⟩
- Benoit Roussel, Richard Macrez, Amandine Jullienne, Véronique Agin, Eric Maubert, et al.. Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Brain - A Journal of Neurology , 2009, 132 (8), pp.2219-2230. ⟨10.1093/brain/awp162⟩. ⟨hal-05509932⟩
- Jose Lopez-Atalaya, Benoit Roussel, Denis Levrat, Jérôme Parcq, Olivier Nicole, et al.. Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity. Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (6), pp.1212-1221. ⟨10.1038/jcbfm.2008.14⟩. ⟨hal-05509935⟩
- Fabian Docagne, Cecilia Gabriel, Nathalie Lebeurrier, Sylvain Lesné, Yannick Hommet, et al.. Sp1 and Smad transcription factors co-operate to mediate TGF-β-dependent activation of amyloid-β precursor protein gene transcription. Biochemical Journal, 2004, 383 (2), pp.393-399. ⟨10.1042/BJ20040682⟩. ⟨hal-05509939⟩
- Pascale Schumann, Valérie Collot, Yannick Hommet, Willy Gsell, François Dauphin, et al.. Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles. Bioorganic and Medicinal Chemistry Letters, 2001, 11 (9), pp.1153-1156. ⟨10.1016/s0960-894x(01)00156-1⟩. ⟨hal-05509941⟩
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